Banned already in more than 60 countries worldwide, endosulfan is used widely on vegetable crops and cotton and has been linked to birth defects and delayed sexual development in children, as well as an increased risk of developing autism. Although not considered a carcinogen, research shows that endosulfan may also contribute to certain types of cancer, in particular breast cancer.

Even though it was re-registered for use in the U.S. under the Bush administration in 2002, PANNA and others have been pushing to remove endosulfan from the market because of documented evidence of health damage to farm workers as well as people and wildlife living near exposed soil and water. The EPA is now working with the sole manufacturer of endosulfan in the U.S. to establish a timeframe that would allow farmers to come up with effective alternatives to endosulfan use.